Exosomes and platelet-rich plasma (PRP) are both popular treatments in the field of regenerative medicine and aesthetics. While they have similarities, there are some key differences between them.


Exosomes are tiny extracellular vesicles derived from stem cells or other cells, such as mesenchymal stem cells. They contain various proteins, lipids, and nucleic acids. Exosomes have gained attention for their potential regenerative properties and ability to enhance tissue repair and rejuvenation. In aesthetic applications, exosomes are often used topically or injected into the skin to promote collagen production, improve skin texture, and reduce the appearance of wrinkles.

Platelet-rich plasma (PRP)

On the other hand, PRP is derived from your own blood. It involves isolating the platelet-rich plasma component, which contains growth factors and cytokines. PRP is obtained by taking a blood sample, processing it to separate the plasma, and then concentrating the platelets. The resulting PRP can be injected into the skin or used in conjunction with techniques like microneedling. PRP is known for its ability to promote tissue regeneration, stimulate collagen production, and enhance skin rejuvenation.

Differences between Exosomes and Platelet-rich plasma (PRP)

While exosomes and PRP are both used for aesthetic purposes, there are a few distinctions:


Exosomes are derived from stem cells or other cells, while PRP is derived from your own blood.


Exosomes contain various molecules, including proteins and nucleic acids, while PRP primarily consists of growth factors and cytokines.

Mechanism of action

Exosomes are believed to exert their effects by transferring their cargo of cellular components to target cells, influencing their behavior. In contrast, PRP primarily stimulates cell signaling through the growth factors and cytokines present.


Exosomes are typically obtained from cell culture or purchased from specialized companies, while PRP can be produced on-site using your own blood.

Help finding what is best for you

Choosing between exosomes and PRP for facial treatments depends on various factors, including the specific goals of the treatment, your medical history, and the recommendations of your healthcare provider. Consult with a qualified professional at Refined Women’s Wellness who can assess your individual needs and guide you toward the most appropriate option. Book your complimentary consultation here.